Nicotine dependence

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Nicotine is a psychoactive substance, that is, it has the ability to influence the psychoemotional state of a person. Getting into the body together with tobacco smoke, it is absorbed into the blood and reaches the brain within 7-10 seconds. Here it binds to the nicotine receptors of neurons, which contain acetylcholine, a neurotransmitter or transmitter of nerve impulses. Nicotine acts like acetylcholine and causes brain receptors to secrete so-called “hormones of joy” and stimulant substances – serotonin, norepinephrine, dopamine, gamma-aminobutyric acid and glutamate. Therefore, smoking gives the smoker pleasure, causes emotional uplift, suppresses hunger, increases the activity of the cardiovascular system. However, at the same time, the process of tobacco addiction formation is launched, which includes two main components – physical and psychological.

Physical component

Physical dependence on cigarettes is understood as the adaptation of the central nervous system when smoking. After smoking a cigarette, a person notes that the craving for smoking has decreased, but does not suspect what is happening in the brain.

The actions of nicotine cannot be controlled by the central nervous system6, and the receptors that it affects gradually lose sensitivity to it1,6, their number increases, which is manifested by an even greater, acute desire to smoke another cigarette. This is how chronic consumption starts. At the initial stage of addiction formation, the smoker is faced with the fact that in order to recreate sensations of the same intensity, it is necessary to increase the dose of nicotine. When the body adapts to this dose, the smoker begins to need the usual, individual dose of nicotine not so much for pleasure as in order to feel a neutral state or warn.

Psychological component

Often a person stops noticing the fact of smoking and how many cigarettes he smokes, but he continues to smoke. The fact is that over time, a regular smoker develops behavioral automatism and so-called “smoking rituals”. With their help, he tries to cope with stress, fatigue, or just lights up when he is bored. All this forms a certain behavior, reinforces, and then gradually strengthens the habit of smoking. So the physical dependence on tobacco is joined by a psychological one.

Hereditary predisposition

The genetic component influences human behavior. Hereditary “vulnerability” is transmitted with genes, which is associated with a violation of the function of neurotransmitters in the brain and underlies addictions, including to tobacco.6 According to some estimates, a genetic factor may contribute to the development of addiction in about 50% of cases.

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La nicotina es una sustancia psicoactiva, es decir, tiene la capacidad de influir en el estado psicoemocional de una persona. Al entrar en el cuerpo junto con el humo del tabaco, se absorbe en la sangre y llega al cerebro en 7-10 segundos. Aquí se une a los receptores de nicotina de las neuronas, que contienen acetilcolina, un neurotransmisor o transmisor de impulsos nerviosos. La nicotina actúa como la acetilcolina y hace que los receptores cerebrales secreten las llamadas “hormonas de la alegría” y sustancias estimulantes: serotonina, norepinefrina, dopamina, ácido gamma – aminobutírico y glutamato. Por lo tanto, fumar le da placer al fumador, causa elevación emocional, suprime el hambre, aumenta la actividad del sistema cardiovascular. Sin embargo, al mismo tiempo, se inicia el proceso de formación de adicción al tabaco, que incluye dos componentes principales: físico y psicológico.

Componente físico

La dependencia física de los cigarrillos se entiende como la adaptación del sistema nervioso central al fumar. Después de fumar un cigarrillo, una persona nota que el deseo de fumar ha disminuido, pero no sospecha lo que está sucediendo en el cerebro.

Las acciones de la nicotina no pueden ser controladas por el sistema nervioso central6, y los receptores a los que afecta pierden gradualmente sensibilidad a ella1,6, su número aumenta, lo que se manifiesta por un deseo aún mayor y agudo de fumar otro cigarrillo. Así es como comienza el consumo crónico. En la etapa inicial de la formación de la adicción, el fumador se enfrenta al hecho de que para recrear sensaciones de la misma intensidad, es necesario aumentar la dosis de nicotina. Cuando el cuerpo se adapta a esta dosis, el fumador comienza a necesitar la dosis habitual e individual de nicotina no tanto por placer como para sentir un estado neutro o advertir.

Componente psicológico

A menudo, una persona deja de notar el hecho de fumar y cuántos cigarrillos fuma, pero continúa fumando. El hecho es que con el tiempo, un fumador regular desarrolla automatismo conductual y los llamados “rituales de fumar”. Con su ayuda, trata de lidiar con el estrés, la fatiga o simplemente se ilumina cuando está aburrido. Todo esto forma un cierto comportamiento, refuerza y luego fortalece gradualmente el hábito de fumar. Así que a la dependencia física del tabaco se une una dependencia psicológica.

Predisposición hereditaria

El componente genético influye en el comportamiento humano. La “vulnerabilidad” hereditaria se transmite con genes, lo que se asocia con una violación de la función de los neurotransmisores en el cerebro y subyace a las adicciones, incluido el tabaco.6 Según algunas estimaciones, un factor genético puede contribuir al desarrollo de la adicción en aproximadamente el 50% de los casos.