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Pharmacological properties
Pharmacodynamics. This drug protects the mucous membrane of the esophagus, stomach and duodenum. In studies of the use of a single dose in vitro by the Water method, the total acid neutralizing ability (titration at pH 1) was 44.9 mmol of H+ ions.
The drug is not radiopaque.
Use as an antacid and adsorbing agent.
Pharmacokinetics. Magnesium and aluminum hydroxides are antacids of local non–systemic action, the absorption of which is of little use under normal conditions.
Indications
Treatment of heartburn and acid reflux in adults and children from 15 years.
Contraindications
Severe forms of renal insufficiency (since this remedy contains magnesium), hypersensitivity to the components of the drug. Alzheimer’s disease, habitual constipation, chronic diarrhea, severe abdominal pain of unspecified genesis, hypophosphatemia.
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Propiedades farmacológicas
Farmacodinámica. Este medicamento protege la membrana mucosa del esófago, el estómago y el duodeno. En estudios del uso de una dosis única in vitro por el método del Agua, la capacidad neutralizante ácida total (titulación a pH 1) fue de 44,9 mmol de iones H+.
El medicamento no es radiopaco.
Úselo como antiácido y agente adsorbente.
Farmacocinética. Los hidróxidos de magnesio y aluminio son antiácidos de acción local no sistémica, cuya absorción es de poca utilidad en condiciones normales.
Indicacion
Tratamiento de la acidez estomacal y el reflujo ácido en adultos y niños a partir de 15 años.
Contraindicaciones
Formas graves de insuficiencia renal (ya que este remedio contiene magnesio), hipersensibilidad a los componentes del medicamento. Enfermedad de Alzheimer, estreñimiento habitual, diarrea crónica, dolor abdominal intenso de génesis no especificada, hipofosfatemia.
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